The space health intelligent protection system is designed based on the health and safety needs of human settlements in the post-epidemic era, and intelligently realizes efficient virus barrier and space purification through the integration of killing technologies such as hydroxyl, ozone and photocatalyst. Under the condition of human-machine coexistence, the number and activity of viruses and microorganisms in the space are minimized, adaptive design is carried out through different space requirements, and the task of guarding the health of human settlements in the space is completed through intelligent interaction. The design without consumables also enables the product to be used continuously for a long time, and at the same time, the cost of living becomes controllable.